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Home / Sjögren’s Syndrome Information / Diagnosis of Sjögren’s Syndrome / Ultrasonography of the Major Salivary Glands

Ultrasonography of the Major Salivary Glands

With the use of high-frequency sound waves, the ultrasound machine can examine the structure of the major salivary glands. These glands include the parotid glands (located over the angle of the jaw) and the submandibular glands (located under the mid-portion of the jaw bone on each side). This is the same type of ultrasound machine that is used to visualize the fetus in a pregnant woman. A smooth probe coated with gel is placed over the glands and pictures are taken by the ultrasonographer. As many as one-half to two-thirds of patients with Sjögren’s syndrome have characteristic changes in the structural features of their glands (resulting from inflammation). These changes can be successfully detected by ultrasonography and help secure the diagnosis of Sjögren’s syndrome. These structural changes also correlate with disease severity and can provide useful information about the expected course of the disease. On occasion, patients with enlargement or an isolated growth of their glands will require a biopsy. This can be done with a special needle, using ultrasound to guide its placement in the gland.

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All information contained within the Johns Hopkins Jerome L. Green Sjogren’s Center website is intended for educational purposes only. Physicians and other health care professionals are encouraged to consult other sources and confirm the information contained within this site. Consumers should never disregard medical advice or delay in seeking it because of something they may have read on this website.

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Dr. Alan Baer in Chair in Front of Brick Wall Discussing Sjögren’s Syndrome

In this five-part video series on Sjögren’s syndrome, Dr. Alan Baer validates those who suffer from this disease, and informs those who don’t, about the common misconceptions and challenges that Sjögren’s syndrome patients face every day.

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