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Home / Research

Research

The Jerome L. Greene Sjögren’s Disease Center at Johns Hopkins is a leader in Sjögren’s disease research and care. For decades, our physicians and researchers have worked to deepen the understanding of this complex disease and improve outcomes for our patients. Our research has earned international recognition and continues to advance new ideas and discoveries in the field.

We invite you to join us in the effort to develop better treatments for everyone affected by Sjögren’s disease.

Clinical Trials

Actively Enrolling

  • National Sjögren’s Disease Registry

Upcoming

  • RISE THERAPEUTICS: clinical trial
  • NOVARTIS THALASSA: A randomized, double-blind, placebo-controlled, 2-arm multicenter Phase III study to assess the efficacy and safety of ianalumab in participants with Sjogren’s disease with high symptom burden

Current

  • POETYK SjS-1: A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Deucravacitinib in Adults with Active Sjogrens Syndrome
  • NEPTUNUS: A randomized, double-blind, placebo controlled, multicenter phase III study to assess the efficacy and safety of ianalumab in patients with active Sjögren’s syndrome
  • ARGENX UNITY: A Phase 3 Randomized, Double-Blinded, Placebo-Controlled Multicenter Trial with Open-Label Extension to Evaluate the Efficacy, Safety, and Tolerability of Efgartigimod PH20 Subcutaneous Administered by Prefilled Syringe in Adult Patients with Primary Sjögren’s Disease

Past

  • STAMP: Sjogren’s Team for Accelerating Medicines Partnership
  • SICCA: Sjögren’s International Collaborative Clinical Alliance
  • SSDE: Sjögren’s Syndrome Screening Dry Eye
  • TWINSS: A 48-week, 6-arm, randomized, double-blind, placebo-controlled multicenter trial to assess the safety and efficacy of multiple CFZ533 doses administered subcutaneously in two distinct populations of patients with Sjögren’s Syndrome

If you are interested in participating in research, or want to learn more, please contact:

Jen Reed
jreed52@jhu.edu
P: 410-550-9821
P: 410-550-6492

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All information contained within the Johns Hopkins Jerome L. Green Sjogren’s Center website is intended for educational purposes only. Physicians and other health care professionals are encouraged to consult other sources and confirm the information contained within this site. Consumers should never disregard medical advice or delay in seeking it because of something they may have read on this website.

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Dr. Alan Baer in Chair in Front of Brick Wall Discussing Sjögren’s Syndrome

In this five-part video series on Sjögren’s disease, Dr. Alan Baer validates those who suffer from this disease, and informs those who don’t, about the common misconceptions and challenges that Sjögren’s disease patients face every day.

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