Gynecologic symptoms are an important, though often overlooked, aspect of Sjögren’s disease. Vaginal dryness is common during menopause, but women with Sjögren’s disease report it 2 to 3 times more often than women of the same age without Sjögren’s disease.
Menopause can cause vaginal atrophy, which results from a decline in estrogen levels. Sjögren’s disease may worsen these symptoms, leading to thinning of pubic hair, loss of vaginal folds, decreased vaginal moisture, and narrowing of the vaginal opening. Symptoms may include:
- Vaginal burning or itching
- Pain with intercourse
- Vaginal spotting or discharge
These symptoms can also be caused by other conditions, including vaginal infections, skin disorders, or irritation from soaps, detergents, lubricants, or sanitary products. Vaginal bleeding may also be a sign of certain gynecologic cancers, so evaluation by a gynecologist is important.
The treatment of vaginal dryness in the setting of Sjögren’s disease includes the use of vaginal moisturizers, water soluble lubricants during sexual activity, and vaginal estrogen creams. For more information about treatment, see of Management of Gynecologic Problems.

